Carl Johan disputerade 2004 om dGEMRIC, en metod att bedöma broskkvalitet. Från att i början mest ha studerat knäleden har höften fått allt större fokus även i

The dGEMRIC indexof each hip was calculated as the mean T1Gd of its ROI, excluding voxels with T1Gd >1300 ms, according to standard protocol at our institution. dGEMRIC indices were then adjusted for BMI to correct for differ-ences in distribution volume using the formula described by Tide-rius et al.26. Two investigations were excluded due to

List of 7 DGEMRIC definitions. Top DGEMRIC abbreviation meanings updated February 2021 Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) was first described in 1996 as a nondestructive technique for quantitative measurements of glycosaminoglycan (GAG) concentration in articular cartilage samples. Abstract Background: dGEMRIC (delayed Gadolinium Enhanced Magnetic Resonance Image of Cartilage) is a well-established technique for cartilage quality assessment in osteoarthritis at clinical field strengths. The method is robust, but requires injection of contrast agent and a cumbersome examination procedure. Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) is a validated imaging technique to evaluate cartilage quality in vivo.

dGEMRIC indices similar to those from their matched controls and in the normal range for hip cartilage. In all but one of the eight subjects the anterior dGEMRIC index was lower than that in the posterior region. Average T1 for Four Slices Patient T1 (ms) Control T1 (ms) No. Sex/Age Anterior Posterior Sex/Age Anterior Posterior Delayed gadolinium-enhanced magnetic resonance imaging of cartilage, abbreviated dGEMRIC, can be used to estimate the GAG content of cartilage. A contrast medium is used, the concentration of which in the cartilage is inversely proportional to the amount of GAG. 2018-04-01 · Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) is a validated imaging technique to evaluate cartilage quality in vivo. dGEMRIC is estimating the content of glycosaminoglycans (GAG) which is essential for the biomechanical properties of the cartilage and decreases early in the OA process 14. Background The dGEMRIC (delayed Gadolinium-Enhanced MRI of Cartilage) technique has been used in numerous studies for quantitative in vivo evaluation of the relative glycosaminoglycan (GAG) content in cartilage.

28 patients (mean age, 42.3 years) underwent T 2 mapping and dGEMRIC at least 1.5 years 2014-11-01 The dGEMRIC technique can be easily implemented clinically by using a standard 1.5 or 3.0 T magnet. Although the duration of the total acquisition time (up to 2 hours) diminishes its attractiveness for clinical use, dGEMRIC has potential value in clinical trials, where it has shown the ability to demonstrate changes in morphologically intact cartilage that may be predictive of progression to dGEMRIC Index could not be determined due to extreme cartilage thinning.

2016-10-05

The characteristic resistance to compressive forces of healthy cartilage relies on high GAG content. dGEMRIC indices similar to those from their matched controls and in the normal range for hip cartilage.

Delayed gadolinium enhanced magnetic resonance imaging of cartilage (dGEMRIC) is a technique to evaluate cartilage quality by estimation of glycosaminoglycan (GAG) content, a low dGEMRIC index indicates low cartilage quality. The characteristic resistance to compressive forces of healthy cartilage relies on high GAG content.

Från att i början mest ha studerat knäleden har höften fått allt större fokus även i Vidare kan man med kontrastmetoder som gadoliniumförstärkt MR (dGEMRIC) bedöma.

Medicinsk service, dGEMRIC undersökning: 25 st a 6000kr. Gånganalys undersökning: 30 st a 6000kr, 330 000. Utrustning, Patientersättning 55 st a 450kr för Enhanced MRI of Articular Cartilage). dGEMRIC. Bashir et al.
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Also regression analysis was performed to show the influence of local repair on cartilage quality at distant locations in the knee. The dGEMRIC index (mean ± sd) at four times (min ± sd) after intravenous injection of double dose Magnevist. The dGEMRIC index was 20–30 % lower in the patients with early OA compared to healthy volunteers (P < 0.003) at all time points, with largest difference at the earlier time points due to faster wash-in of the contrast in the OA cartilage.
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2018-04-01 · Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) is a validated imaging technique to evaluate cartilage quality in vivo. dGEMRIC is estimating the content of glycosaminoglycans (GAG) which is essential for the biomechanical properties of the cartilage and decreases early in the OA process 14.

Though MRI T2 mapping is capable of assessing collagen organization [9], the dGEMRIC technique can indir-ectly reflect the proteoglycan concentration [10, 11]. using 3D dGEMRIC at two different doses of the contrast agent Gd-DTPA2-. Methods: The right knee in 12 asymptomatic volunteers was examined using a 3D Look-Locker sequence on two occasions after an intravenous injection of a double or triple dose of Gd-DTPA2-(0.2 or 0.3 mmol/kg body weight). The relaxation time (T 1) and relaxation rate (R 1 =1/T viously reported relating dGEMRIC to radiographic indices6.

2014-11-01

RESULTS: There was a significant difference in the mean dGEMRIC indices of the medial compartment between injured and uninjured knees (P<0.007). On average, there was a 13% decrease in the dGEMRIC index of the injured knee compared to the uninjured knee. There were no significant effects due to test order (P=0.800) or cartilage location (P=0.439). What does DGEMRIC stand for?

Standardized dGEMRIC maps of the weight-bearing portion of a representative hip articular cartilage, superimposed to GRE coronal images. Values smaller than zero indicate GAG concentration lower The dGEMRIC MR T1 map is reconstructed from images acquired consec- protocol lasted approximately 15 min. utively with different inversion times (TIs). In patients, the dGEMRIC protocol [10] was performed Automated image registration may improve dGEM- twice with an interval of 7 days (range 5–14 days).